Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change clover dating measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.
Recently, it had been reported that the fresh sodium (Na)/potassium (K) ratio is associated with blood circulation pressure (BP) from inside the a corner-sectional research [1,dos,step three,4]. It is expected due to the fact high Na and you can K intake try identified become related to high and you will reasonable BP, respectively [5,6,7]. As well, research has been held toward resource thinking and you will facts contributing to the newest Na/K ratio prior to now seasons [8, 9].
During the a residential area form, it is hard for us to assess the actual Na consumption as Na consumption are typically examined by the 24-h pee range. In the event several equations having estimating Na intake otherwise K consumption using casual room pee have been has just dependent, these equations aren’t appropriate adequate to promote feedback on the someone [10,eleven,12]. Additionally, because equation demands measuring Na, K, and you will creatinine accounts during the a research, it will require several weeks to obtain the results for individuals. Even if participants realize that sodium prevention is perfect for minimizing BP, he has not a way regarding evaluating the Na level.
Has just, good Na/K ratio care about-keeping track of unit using spot pee are established . Although it failed to assess the genuine Na consumption top, it does promote opinions concerning your urinary Na/K balance in a few minutes. Moreover, an enthusiastic interventional otherwise observational study using this type of screen recommended this will be a good unit to imagine the latest urinary Na/K ratio [13, 14].
For this reason, although we have no solution to gauge the Na/K ratio when you look at the wellness checkup configurations, we thought that examining this new urinary Na/K ratio for the a healthcare checkup site may have the potential to include feedback on the general populace regarding their Na/K ratio that will impact perception alter, improvement in step, Na/K proportion cures, and you can BP avoidance. Inside data, we reviewed if the urinary Na/K ratio transform mentioned with the Na/K proportion dimensions unit was with the BP change separate away from confounding affairs including body mass index (BMI) transform and alter within the alcoholic beverages intake and you may compared the fresh BP level and you will urinary Na/K ratio within community height.